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InChiKey: ABCVHPIKBGRCJA-UHFFFAOYSA-N
In vitro: Tivozanib markedly inhibited the ligand-induced phosphorylation of VEGFR1\2 and 3 with the IC50 value of 30 nM\6
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Smiles: NC(=O)C1C=[N+](C=CC=1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O
PubMed PMID: 20053781
IDO1-IN-2 23520 InChiKey: ABCVHPIKBGRCJA-UHFFFAOYSA-NIDO1 IN 2 (compound 16) is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse) and 28 nM (rat), respectively. IDO1 IN 2 has anti cancer activity. Product information CAS Number: 2346614 58 0 Molecular Weight: 364. 33 Formula: C15H17FN6O4 Chemical Name: 2 [(4 {N' [(7S) 4 fluorobicyclo[4. 2. 0]octa 1,3,5 trien 7 yl] N hydroxycarbamimidoyl} 1,2,5 oxadiazol 3 yl)amino] N (2 hydroxyethyl)acetamide Smiles:
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